Regulatable Acetylcholine-Producing Fibroblasts Enhance Cognitive Performance
نویسندگان
چکیده
منابع مشابه
Homogeneous tetracycline-regulatable gene expression in mammalian fibroblasts.
The expression of transfected genes in mammalian cells is rapidly repressed by epigenetic mechanisms such that, within a matter of weeks, only a fraction of the cells in most clonal populations still exhibit detectable expression. This problem can become prohibitive when one wants to express two ectopically introduced genes, as is necessary to establish cell lines that harbor genes regulated by...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2006
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2005.08.001